Medication

Yohimbine Hydrochloride

Structure

One tablet of Yohimbine hydrochloride contains 5 mg of the same active substance.
Excipients: lactose monohydrate, starch, hypromellose, calcium stearate, celactose.

Release form

Yohimbina hydrochloride tablets are white or pale yellow. The drug is available in 50 tablets in a plastic jar or plastic container; one such can or container in a pack of paper.

Pharmachologic effect

Stimulates potency.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Yohimbine hydrochloride enhances potency (aphrodisiac) and is an alkaloid obtained from the bark of a tree Corynanthe.
The action is due to selective suppression of α2-adrenergic receptors. It activates adrenergic neurons in the brain, has a psychostimulating effect. It is likely that it also affects dopaminergic, serotonergic and cholinergic system.

Yohimbine hydrochloride stimulates sexual behavior and restores reduced sexual activity due to stress and impaired erection.

The therapeutic effect is explained by the effects of Yohimbine hydrochloride, affecting the nervous system. Perhaps enhances the blood circulation of the penis and has a direct effect on the tissues involved in an erection.

Pharmacokinetics

Fully absorbed in the intestine within an hour. The highest concentration in the blood occurs after 40-70 minutes. When taken orally in the recommended doses, the accumulation of the drug in the body does not occur. The elimination half-life depends on the accepted dose.

82% of Yohimbine hydrochloride binds to plasma proteins. Metabolized in the liver. Two major metabolites are known: active 11-hydroxyohymbin and weakly active 10-hydroxyohymbin.

Indications for use

Functional and psychogenic therapy impotencemale menopause, atony Bladder.

Contraindications

  • Hypersensitivity to Yohimbine hydrochloride or other components of the drug.
  • Pronounced arterial hypotension.
  • Severe damage to the liver and kidneys.
  • Therapy adrenomimetics.
  • This medicine is not intended for use by women and children.

Side effects

  • Cardiovascular Disorders: tachycardiaincreasing pressure.
  • Neurological disorders: tremor, dizziness, headache, sleep disturbanceirritability, sweating.
  • Digestive system disorders: loss of appetite, nausea and vomiting, diarrhea.
  • Skin reactions: hyperemia.
  • Other: decline diuresis, priapism, allergic reactions.

Instructions for use (Method and dosage)

The instruction prescribes to take the drug orally during meals, washed down with water and without chewing. 1-2 tablets one to three times a day.

The dose is recommended to be selected individually. The initial dose is 2.5 mg 3 times a day, the maximum is 1-2 tablets three times a day.
The effect in some cases occurs after a few weeks. The duration of therapy depends on the clinic of the disease and can be 4 weeks.

Overdose

Symptoms of peridosage. 30-45 minutes after taking an excessive dose appear generalized paresthesiaweakness, memory impairment, dizziness, headache, tremorpressure increase tachycardia, feeling of fear, increase in level norepinephrine in the blood, nausea, mydriasisvomiting, sweating. These symptoms may persist for 2-3 hours.

Treatment: stop taking the drug, rinse the stomach, then take Activated carbon. How can an antidote be used? TOlonidine, which eliminates the mental effects and disorders of the sympathetic nervous system.

For therapy hypertensive crisis recommended β-blockers in conjunction with α-blockers or peripheral vasodilators. In case of overdose, it is forbidden to use antipsychotics phenothiazine series.

Interaction

In conjunction with clonidine the effects of drugs are mutually neutralized.

Clopiramine increases the concentration of Yohimbine hydrochloride in blood plasma.

Yohimbine hydrochloride enhances the action antidepressants and increases the risk of side effects caused by them.

Joint reception with tranquilizers weakens the activity of the latter.

Terms of sale

The drug can be purchased only with a prescription.

Storage conditions

  • Store at a temperature not exceeding 25 degrees.
  • Keep out of the reach of children.

Shelf life

Three years.

Special instructions

The composition of the drug includes lactose and patients with galactose intolerance, glucose galactose malabsorption syndromeor lactase deficiency it is forbidden to use this tool.

Analogs

Matches for ATX Level 4 code:TornetisOlmax StrongTaxiereDynamicallyRevazioCoverjectLevitraCialisTentex ForteRailisViagraSildenafilZidenaRange

The closest in composition analogues: Yohimbine "Der Spiegel", Yohimbe Evalar, Yohimbine Forte, Super Yohimbe Plus.

Yohimbine slimming

Sometimes the drug is used in sports nutrition as a stimulator of the fat burning process (including bodybuilding).

Therefore, the question often arises "how to take Yohimbine for weight loss?" It is believed that a safe dose of 10-20 mg, taken separately with food in several doses. However, doctors do not recommend taking this drug for other purposes, due to possible side effects.

Yohimbine Hydrochloride Reviews

Numerous positive reviews are known about Yohimbine, including when used for weight loss in bodybuilding and during sports. It should be remembered that before taking the drug, you must always consult a doctor.

Price of yohimbine hydrochloride

Where to buy yohimbine hydrochloride? This drug is sold in the pharmacy network; you may need a doctor's prescription to purchase it.

In Russia, the price of Yohimbine in a pharmacy is 189 - 225 rubles, in Ukraine - 40-49 hryvnias. Buy Yohimbine Spiegel and other analogues of the drug will cost more and it is more difficult to find them in the free market.

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