Capsule pharmaceutical preparation contains: retinol palmitate (vitamin A) - 100,000 IU; alpha tocopherol acetate (vitamin e) - 0.1 g; sunflower oil as an auxiliary substance. The gelatin shell contains the following components: gelatin; glycerol; methyl parahydroxybenzoate (E 218); propyl parahydroxybenzoate (E 216).
Structure vitamins as an injection (1 ml): acetate retinol- 0.035 g; alpha tocopherol acetate - 0.1 g.
Structure Aevit cream: vitamin A; vitamin e; phenoxyethanol and ethylhexiglycerin; blend of extracts (raspberries, rosemary, edelweiss); propylheptyl caprylate; propylglyceryl-3 metiglucose distearate; capric / capric / triglycerides; erucate oleyl; higher fatty alcohols; glyceryl stearate; glycerol; demineralized water.
Aevit vitamins in drugstores are delivered in three main pharmaceutical forms:
- Soft gelatin capsules spherical or spherical in yellow or light brown color with a clearly defined dividing line. The shell is filled with an oily medicinal fluid, the color of which can vary from light yellow to dark yellow, which does not indicate the unsuitability of the drug. Capsules are packed in glass jars of 25 pieces each or in blister packs of 10 pieces each.
- Liquid injection solution in ampoules, calculated on 1 ml of a vitamin remedy. 10 pieces and an abstract are put in a cardboard box.
- Aevit Nourishing Cream for face in bottles of 50 ml. 1 bottle and instructions in each carton.
Aevit is a combined drug whose active components are involved in a large number of different metabolic processes and physiological reactions in the body. The therapeutic possibilities of a pharmaceutical preparation are striking in its breadth, because vitamin complex at the same time possesses antioxidant, and immunomodulatoryproperties that stimulate the reproduction of epithelial cells and tissue growth, and therefore contributes to reparativeand regenerativecapabilities of individual organs and systems.
The drug improves the blood supply to the microvasculature, normalizes the permeability of the vascular wall throughout the circulatory system, increases the quality of trophic processes. Biologically active components are necessary for the normal functioning of the visual and reproductive systems, the proper course of protein and lipid metabolism. The mechanism of action of the drug should be considered separately for each vitamin.
Retinol palmitate (or acetate in some variations of Aevit), better known as vitamin A - this is fat soluble chemical compound. It is believed that most of the effects of this component are concentrated on the organs of vision, but this is only half the true biochemical picture of the interactions of vitamin A. Of course, the biological component takes an invaluable part in the formation of the visual signal, as it promotes the transformation of the protein structure of opsin into rhodopsin. This conversion of proteins is especially important for the eyes in low light.
Another significant group of therapeutic effects of vitamin A is its effects on the immune system. First of all, a general strengthening effect should be noted, then, upon a more detailed examination, they are striking:
- gain myelopoiesis;
- revitalization macrophage system;
- increased factor humoral and cellular immunity;
- strengthening the protective mechanisms of the mucous membrane of the gastrointestinal system and respiratory tract.
The regulatory abilities of vitamin A extend not only to the main types of metabolism (protein, fat and so on), but also to the functioning of the glands of external and internal secretion, including the lacrimal, sebaceous and sweat glands. In combination with other effects, this allows you to use Aevit for hair as a cosmetic and therapeutic agent, to prevent the possible destruction of hair rods and bulbs, to provide the structural units of the hair with all the necessary trophic substances.
From the point of view of organic chemistry, retinol is a molecule with a large number of unsaturated bonds, which allows vitamin A to participate in various redox reactions. The therapeutic effects of this particular feature of a biologically active substance when applied to the skin externally are especially clearly visible:
- holds the necessary amount of intracellular fluid;
- plays an important role in education glycosaminoglycans;
- stimulates reproduction epithelial cells, which allows you to rejuvenate the skin and get rid of wrinkles;
- is having antioxidant effect;
- improves capillary circulation and local defense mechanisms, because Aevit for acne is popular among a young category of patients.
Alpha tocopherol or vitamin e, the second active ingredient of the pharmaceutical drug Aevit, is a fat-soluble chemical compound that is part of the natural metabolism human body and, like vitamin A, has many useful therapeutic effects with additional exogenous intake.
First of all, Wikipedia, the free encyclopedia of global knowledge on the Internet, notes it antioxidant activity. That is, the constituent component of the drug slows down the oxidation of unsaturated fatty acids and, thus, reduces the formation of peroxide compounds, which prevents red blood cell hemolysis and the destruction of other cellular structures. Also, the mechanism of antioxidant activity of vitamin E includes its ability integrate into membranes, preventing contact with oxygen and free radicals circulating in the blood. This property of alpha-tocopherol causes the use of Aevit for the skin around the eyes, the problem area of the face retains youth and elasticity much longer if you use vitamin E regularly.
The active active ingredient of a pharmaceutical preparation has extensive effects on cardiovascular system. Alpha-tocopherol is a cofactor of various enzymatic systems of the body, which is realized in such positive therapeutic effects as stimulation of microcirculation, normalization of trophic processesin tissues, improving capillary blood flow and permeability of this segment of the vascular bed. This leads to the use of Aevit as a healing measure for eyelashes and for nails, because the derivatives of the skin are primarily affected by various pathological conditions due to the peristributive ability of the vascular system.
Has vitamin E effects on protective function organism. In particular Alpha tocopherol acetate stimulates the cellular and humoral parts of the immune system, the activity of T-lymphocytes increases significantly. Due to the inhibition of phospholipase A2 lysosomes, the potential for destruction of the phospholipid layer of cell membranes is eliminated.
Strengthening the protective functions is an incredibly important task for everyone, because it is much easier to prevent a disease than to sanitize a pathological focus, which is why Aevit tablets are best suited due to the content of vitamins A and E.
Pharmacodynamics and pharmacokinetics
The pharmacokinetic capabilities of the combined drug are practically independent of the chosen form of release after entering the systemic circulation, therefore it is enough to consider only one example. Capsules are well absorbed from the digestive tract, after which they are transported to the lymph and blood plasma, where they bind to specific carrier proteins and "travel" to organs and tissues. A quantitative excess of vitamin A is retained in the liver in the form of palmitic acid esters, and the main stages of its biotransformation before the elimination stage take place here. Excretion is slow - only 34% of the dose taken is removed within 3 weeks.
An excess of another active ingredient, vitamin E, depositedeverywhere in body tissues. Metabolic processes occur through the conversion of the natural structure of the component of the drug into quinine, after which they are removed with urine. Unchanged, vitamin E can be eliminated with bile.
- atherosclerosis vascular bed;
- systemic lupus erythematosus;
- endocarditis obliterans and endarteritis;
- regional or systemic disorders of microcirculation and trophic tissue;
- peripheral neuropathy;
- atrophyoptic nerve;
- hemeralopia (night blindness);
- necrotizing myopathy;
- pigmentary retinitis.
Indications for use also include pathological conditions when the intake of vitamins A and E with food is significantly reduced, which allows Aevit to be used in the treatment process of the following nosological units:
- chronic diarrhea;
- diseases of the small intestine of various origins (celiac disease, Crohn's disease, malabsorption syndrome and so on);
- cystic fibrosispancreas;
- cirrhosis of the liver and pathologies that impede the physiological flow of bile into the lumen of the digestive tube;
- acute and chronic infectious diseases;
- idiopathic weight loss;
- unbalanced or malnutrition;
- chronic stress;
- addiction, alcoholism and nicotine addiction.
- hypersensitivity in the active components of the vitamin complex;
- chronic glomerulonephritis;
- chronic circulatory failure.
Contraindications to Aevit vitamins do not include a number of nosological units in which the use of a pharmaceutical preparation is recommended only under the supervision of qualified medical personnel. The list of such diseases is as follows:
- myocardial infarction;
- thromboembolismor the risk of its development;
- heavy forms atherosclerosis coronary arteries;
- acute and chronic inflammatory diseases of the kidneys of a non-specific nature.
The use of Aevit vitamins, as a rule, is well tolerated by patients, because the active components of the pharmaceutical preparation are part of the physiological metabolism of the human body and are required for normal development. In isolated cases, side effects can be observed in the form of one of the following adverse effects:
- nauseaand following her vomiting;
- stool disorders;
- allergic reactions;
- increased irritability;
- aggravation gallstone disease and chronic pancreatitisin the presence of a latent phase of the course of pathologies.
Vitamins Aevit, instructions for use (Method and dosage)
Instructions for use Aevita capsules
How to take Aevit in capsules - orally, swallowing the entire tablet. It is not recommended to chew it or keep it in the oral cavity for a long time, since the gelatin shell, in this case, can be damaged, which will inevitably lead to a decrease in the therapeutic activity of the drug. The standard dosage for the implementation of the entire biochemical potential of the active components is 1 capsule 1 time per day, and the duration of treatment is 30-40 days.
For the prevention of various diseases from the list above, the course of conservative rehabilitation is 20-30 days, but a preventive treatment regimen with the full use of a pharmaceutical preparation for 30-40 days can also be used. Repeated therapy, as in the case of struggle with a clearly defined pathology, it is recommended to carry out no earlier than 3-6 months from the end of the previous course.
How to take vitamins for mastopathy?
Vitamins A and E in large quantities, as, for example, in Aevita, have a positive effect on the hormonal background of the female body and the condition of the mammary glands in particular, which makes the purpose of the pharmaceutical preparation mammologistsrational and pathogenetic, that is, affecting certain links in the development of a nosological unit in various types of diseases of the mammary glands.
The dosage of the drug is 1 capsule per day for a month. Such courses of conservative therapy are carried out twice a year, however, some experts believe that capsules can be taken continuously, since intoxication natural vitamins cannot be. This theory is currently not completely reliable and is not supported by all medical professionals.
Method of application of Aevit vitamins in the form of a solution
This form of drug is used to intramuscular injection, that is, the solution can be introduced into the buttocks, front and side surfaces of the abdomen, shoulders and trapezius muscle, the front surface of the thigh. Before the direct use of the pharmaceutical product, the required amount should be slightly warmed up in order to activate it. The standard dosage is 1 ml 1 time per day, and the duration of the course of conservative treatment is 20 days. With trophic disorders, endocarditis and endarteritis, it is increased to 30-40 days. Redevelopment can be carried out after 4-6 months.
For children, the pharmaceutical preparation is not used for the reasons set forth somewhat below in the corresponding section.
How to use Aevit externally?
To improve the general condition of the skin, get rid of wrinkles, cosmetic and therapeutic effects for the lips are most suitable pharmaceutical wraps. Before manipulation, thorough skin cleansing and massage should be performed. Thus, the selected site will be well prepared for applying the drug, which will slightly increase the therapeutic capabilities of the active components of Aevita.
Next, the contents of the ampoule are mixed with an oily solvent. For this purpose is optimally suited olive oil, because in itself it favorably affects the skin. Apply the resulting mixture to the selected area and rub a little. After that, cover the treated area of the skin with a plastic bag (or cling film), wrap it in a towel and wrap it in warm blankets. Rinse after applying the drug does not need anything, the oil allows Aevit to be well absorbed.
The duration of such manipulation is half an hour, and it can be performed twice a week for two months, after which the necessary therapeutic effect will be noted, and the skin will become smooth, fresh and tender.
How to use cream?
A small amount of ointment should be applied to previously cleansed skin in the direction of natural massage lines. Due to the particular composition of this pharmaceutical form, Aevit can be used both in the morning and in the evening, a couple of hours before bedtime.The course of therapeutic measures lasts for 1-2 months with daily use of the cream, then you should take a break.
Vitamins for hair - how to use at home?
Aevit for hair is used according to the most difficult of the proposed schemes, as it combines the external treatment of the scalp with pre-prepared mixtures and the use of oral capsules of the drug. It is in such a combination that the most accelerated and complete effect is achieved.
To eliminate the problem dry and brittle hair the contents of 1-2 Aevit capsules should be mixed with 2 raw egg yolks or 1 tablespoon of low-fat sour cream. Further, carrying out massaging movements, it is necessary to rub the resulting mixture into the scalp. The exposure of the applied drug is 1.5-2 hours, after which the mask can be washed off using ordinary everyday shampoo. The frequency of such a procedure is 1-2 times a week for three months. To repeat the conservative course, wait at least six months.
In order to accelerate hair growth,a slightly modified recipe is used, for which a liquid injection solution is also suitable. The juice of one medium-sized onion is added to the contents of 1-2 capsules or 1 ampoule and mixes thoroughly until the future mask is homogeneous. The mixture is applied by massaging movements on clean hair, after which it is recommended to wrap your head with a towel or put on a plastic hat and leave it for half an hour. At the end of the procedure, you need to wash your hair with the usual shampoo. The mask shows effectiveness if used twice a week for a month, after which there is a long break, and the procedure is repeated only when strictly necessary.
Aevit tablets or injection for prolonged use may cause vitamin A hypervitaminosis, which is manifested by chronic intoxication with this biologically active substance and is observed as the following symptoms:
- lesions of the central and peripheral nervous system;
- disturbances in sleep and wakefulness;
- sudden increase in cerebrospinal fluid pressure without changing its qualitative composition;
- heart failure;
- increased irritability;
- drynessand cracks in the skin (especially in the area of the feet and palms);
- joint pain
- an increase in the size of the liver and spleen.
There is no specific pharmaceutical antidote for overdosing with Aevit; in case of symptoms of intoxication, the drug shows the therapy of the observed clinical manifestations and immediately calls a qualified specialist to eliminate the pathological condition that threatens the patient’s life.
Terms of sale
You can buy a vitamin preparation without a prescription.
The drug should be stored in a dry place, away from possible direct sunlight, at a constant temperature from 15 to 25 degrees Celsius.
The pharmaceutical preparation is not used in pediatric practice, since hypervitaminosis of one of the active components of Aevit may adversely affect the further development of the child and cause irreversible effects in the growing young body.
Aevit during pregnancy and lactation
Face cream, tablet and injection forms of the pharmaceutical preparation Aevit are contraindicated for use directly during pregnancy and breastfeeding, since an excess of vitamins can adversely affect the developing body of the child, and it is definitely impossible to regulate the intake of a certain amount due to the complex transformation pathways and metabolic chains of the active components of the drug.
The beneficial therapeutic effect of the combined Aevit vitamins is known and clinically confirmed by experienced and qualified specialists with pregnancy planning. The drug is prescribed in advance, before the critical period, in order to deposit the necessary structural elements and not feel the need for them during the period of gestation or lactation. According to antenatal clinics, such preventive measures can protect the expectant mother and child.
Reviews about Aevita
Reviews about Aevita should not be sought in one source on the Internet, since the presence of several pharmaceutical release forms allows you to embrace a fairly wide range of various pathological changes in which the drug is useful with reliably proven therapeutic effect. For example, reviews of Aevit vitamins in tablet form can be found on the cardiology forums.
Most patients who drink Aevit capsules according to various heart or vascular diseases leave positive recommendationsabout this drug. This is achieved, first of all, by the ease of use and the relatively quick implementation of therapeutic properties, because the healing effects are manifested during the course of conservative rehabilitation. Patients note that the quality of life improved significantly after using Aevit.
Doctors' reviews about Aevit capsules advocate for such a useful and effective pharmaceutical product, because such an amount of physiological vitamins contained in certain foods cannot be obtained naturally. Normalized most metabolic processes and metabolic cyclesthat allows you to adjust body adaptive abilities and even influence the pathogenesis of even such a complex disease as atherosclerosis, reducing, and sometimes completely stopping, calcification of the arterial bed.
If you are wondering how well vitamins help for facial skin, then reviews on Aevit cream should be sought at cosmetology and women's forums or medical journals that specialize in skin and sexually transmitted diseases. First of all, it should be noted that face cream is incredibly easy to use at home. Aevit is quickly absorbed and does not leave marks on clothing or stains at the place of application of the ointment, which is the first reason for its widespread use as a remedy for wrinkles or other skin defects.
Another aspect of choosing Aevit cream is its chemical composition, because vitamins A and E are part of the natural metabolism, which provides a broad theoretical and practical basis for proving its therapeutic properties in the process of getting rid of wrinkles, even in the most difficult places. You can safely use the drug for the lips, since even the active absorption of the pharmaceutical preparation only in isolated cases will lead to the development of side effects.
Since the constituent components of Aevita improve trophic processes when applied externally, vitamins for acne often prescribed in adolescence. A cream is used, and not tablets or an injection, since only the local therapeutic effects of biologically active substances are required. In addition, this form of release allows you to minimize the risk of developing an overdose condition, because vitamins A and E are included in the metabolic chains regionally.
How to drink Aevit to improve the quality characteristics of hair or accelerate their growth should be obtained from a professional cosmetologist, since the combination of the oral course and the external use of the pharmaceutical preparation shows really amazing results, as evidenced by the number of female reviews after the use of the drug for hair. It should be noted that depending on the recipe, you can achieve a different end result. Aevit is known to help eliminate problem of brittleness, dryness, excessive oily hairallows accelerate hair growth and solve some other issues.
Aevit's price, where to buy
The price of Aevit, first of all, depends on the form of the pharmaceutical product, regardless of the country of purchase. Ukraine offers to buy a medicine according to such prices:
- the price of Aevit vitamins (gelatin capsules) - 52 hryvnias;
- injection solution - 60 hryvnias;
- face cream - from 70 hryvnias and above.
However, before you buy a pharmaceutical product, it is recommended to additionally find out how much is in the pharmacy of your city, because, for example, Kharkov is an extremely volatile city in this regard, the dynamics of the price of pharmaceutical products of which is a very interesting question for qualified pharmacists and economists.
The cost of the drug in the Russian Federation:
- the price of Aevit tablets is 30-120 rubles;
- ointment for external use - from 150 rubles;
- solution for injection in ampoules - 50-110 rubles.
- Online Pharmacies in Russia
- Online pharmacies in UkraineUkraine
- Online pharmacies in Kazakhstan
- Libriderm aevit gel d / lip moisturizing raspberry juice 20mlR.Cosmetic / Dyne + 150 rub.order
- Libriderm aevit oil d / lip scooter 7mlDina + OOO156 rub.order
- Libriderm aevit growth enhancer aevit nail care product 10mlOOO Oktopas172 rub.order
- Libriderm aevit lipstick hygienic nutritious wild strawberry 4gR.Kosmetik OOO144 rub.order
- Libriderm Aevit soft gel for washing the tube 150mlR.Cosmetic / Dyne + 207 rub.order
- Libriderm Aevit hygienic lipstick bold tube 4g149 rub.order
- Libriderm Aevit hygienic lipstick oily tube 4g151 rub.order
- Libriderm Aevit oil scooter 7ml178 rub.order
- Aevit (caps. No. 20) 73 rub.order
- Libriderm Aevit cream nourishing for hands tube 125ml300 rub.order
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- Aevit №20 capsFP Meligen, ZAO60 rub.order
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- Aevit N10 capsules PAT "Kyivsky Vitamin Factory", metro Kyiv, Ukraine17 UAH order
- Aevit N50 capsules PAT "Kievsky vіtamіnniy zavod", metro Kyiv, Ukraine68 uah order
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- Librederm Aevit 4 g lipstick gig. fatGamma Cosmetics (Russia) 968 tg.order
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- Librederm Aevit 4 g lipstick gig. Gamma Cosmetics (Russia) 968 tg.order