One tablet Ciel contains 50 mg dimenhydrinate, colloidal silicon dioxide, talc, microcrystalline cellulose, magnesium stearate.
The medicine is produced in the form of white round tablets, smooth, biconvex. The letter “A” is stamped on one side of the tablet. In a cardboard bundle 1 contour package, it contains 5 tablets.
Pharmacodynamics and pharmacokinetics
Thanks ability dimenhydrinate block H1-histamine receptors and m-cholinergic receptorsthe medicine is having antiemeticsoft sedative and antihistamine impact on the body. Inhibition of the central nervous system and decrease anticholinergicthe consequences vestibular stimulation.
The drug blocks the vomiting center located in medulla oblongatarelaxes smooth musclesreduces peristalsis intestines and salivary gland activity.
When taking Ciel, the severity of effects due to endogenous influence decreases histamineon the body. The medicine normalizes the permeability of capillaries, which is especially important when allergies(Quincke's edema or urticaria).
With oral administration, the effect of the drug is observed after half an hour, its duration is up to 6 hours.
Dimenhydrinatewell absorbed in Gastrointestinal tract and undergoes metabolic reactions in the liver. The elimination half-life is 3.5 hours, complete elimination is a day.
The active substance Ciel passes into breast milk and overcomes blood-brain barrier. The drug is excreted through the kidneys.
Indications for use
The medicine is prescribed:
- as a prophylactic with seasickness and air sickness;
- at Meniere's disease;
- for the prevention or treatment of disorders vestibular apparatus (dizziness, nausea and vomiting).
The drug Ciel is contraindicated:
- at allergies on its components;
- in the first trimester pregnancy;
- children under 2 years old;
- at epilepsy;
- sick bronchial asthma.
Caution should be exercised:
- patients with prostatic hyperplasia;
- at hyperthyroidism;
- if the patient has angle angle or open angle glaucoma;
- with urinary retention or bladder neck obstruction;
- for diseases of cardio-vascular system.
Usually, a medicine does not cause adverse reactions. Their development is most likely when taking large doses of the drug. Under favorable conditions and a timely reduction in dosage, undesirable effects pass on their own.
- fatigue and weakness, decreased visual acuity and concentration;
- dry mucous membranes, vomiting, diarrhea or constipation;
- drowsiness, insomnia, anxiety;
- nausea, lack of appetite;
- headache, depression;
- Quincke's edema, hives, anaphylactic shock;
- bronchospasm, dysuria, arrhythmia and racing HELL.
Instructions for use Ciel (Method and dosage)
The tablets are taken orally. It is advisable before meals, but with a single use it is not important. The dosage and course of treatment is determined by the attending physician.
For prophylaxis seasickness or before a long flight, it is recommended to take the pill half an hour before the trip. Dosage for adults (from 14 years old) - 1 or 2 tablets, for children over 7 years old - 1 tablet, up to 7 years - half a tablet. If there is an urgent need, the tablet can be taken again after 3-4 hours. The maximum daily dosage for children aged 7 to 14 years is 75 mg of the drug.
For treatment vestibular disorders persons over 14 years of age are prescribed 1-2 tablets of the drug twice a day, half an hour before meals. Children from 7 years - half or one tablet three times a day. The maximum daily dosage for children is 150 mg, for adults - 400 mg.
With an overdose in about 30-120 minutes, a headache occurs, drowsiness, weakness and begins to feel dizzy (taking over 25-250 milligrams per kilogram of weight). Then the pupils can expand significantly, impaired vision, anuriadecreased muscle tone, tachycardiachanges blood pressure, itching of the skin. After some time, the processes of oppression central nervous system will continue. Speech becomes slurred, breathing is weak, possible crampsinvoluntary movements of limbs, ataxia and coma.
Children may develop hallucinations, cramps, up to death.
As a therapy, gastric lavage is indicated, taking enterosorbents. It is necessary to call an ambulance, further treatment will occur in a hospital.
The medicine reduces the effectiveness corticosteroids, anticoagulants, acetylcholine, amphetamine.
Ciel doesn't go well with cardiac glycosides, ethyl alcohol, antipsychotics.
The drug increases plasma concentration theophylline.
The drug enhances the effect on CNS atropinesleeping pills sedatives, catecholamines, tricyclic antidepressants, barbiturates.
Caution should be combined dimenhydrinate from neomycin, amikacin, streptomycin, kanamycin and viomycin.
The risk of reducing visual acuity increases with the combination of the drug with drugs bismuth, analgesics, psychotropic drugs, scopolamine.
Terms of sale
The drug is stored in a cool, dark place, at a temperature of no higher than 25 degrees.
It is highly discouraged to combine Ciel with alcohol.
When taking medication, you should avoid driving and performing precision work.
AnalogsMatches for ATX Level 4 code:DesalHistafenClarisensTelfastEriusClaridolClaritinLoratadineFexofastPeritolDesloratadineLORAHEXALClarotadineRupafinDraminaLordestineLomilanFenkarolKestinLoratec
The most common analogues of the drug: Aviomarine, Dramina, Dimenhydrinate, Tavegil.
During pregnancy and lactation
The active substance of the drug can cause malformations in the fetus, such as inguinal hernia or cardiovascular defects. Therefore, taking the drug is possible only when the benefit to the mother will exceed the risk of complications in the fetus.
Breastfeeding should be discontinued.
Ciel has very good reviews. It is often taken by adults and children to avoid motion sickness in transport, during flights or during boat trips. The medicine is quite effective and well tolerated, it is quite inexpensive.
At the moment, it is impossible to indicate the actual price of the drug.