The composition of all forms of the drug includes the active substance clemastine as clemastine hydrofumarate.
In 1 ml of solution contains 1 mg of active substance. Additional substances are: sodium citrate, ethanol, injection water, propylene glycol, sorbitol.
Tavegil tablets contain 1 mg of the active substance, as well as the following additional substances: povidone, lactose monohydrate, talc, magnesium stearate and corn starch.
The drug is available in tablet form, in the form of a syrup, solution for injection.
Means against allergies, itching. Is derivative ethanolamine, histamine blocker of H1 receptors.
Pharmacodynamics and pharmacokinetics
The main, active ingredient in the drug Tavegil acts clemastine. In addition to anti-allergic effects, it has an m-anticholinergic, sedative effect, reduces the permeability of the vascular wall. The drug does not have a hypnotic effect. Tavegil prevents smooth muscle contraction, development vasodilationcaused by the action of histamine. Clemastine reduces itching, has a local anesthetic effect, inhibits the formation of edema, exudation, reduces the permeability of the capillary wall. During the experiment, it was found that Tavegil does not have teratogenic, mutagenic, carcinogenic effects. When taking dosages 300 times higher than normal, it decreases fertility. After oral administration, the maximum effect is recorded after 6 hours, lasts up to 12 hours. Converted to metabolites in the liver, which are excreted by 45-65 percent in the urine. Also, a small part is displayed unchanged.
From what tablets, and also what are the solution and syrup used for?
The medicine is prescribed for allergic urticariahay fever, allergic rhinitis, eczema, itchy dermatosiscontact dermatitis drug allergyallergies to insect bites. Indications for use of Tavegil are also: hemorrhagic vasculitis, serum sickness pseudo-allergic reaction, anaphylactic shock, acute iridocyclitis.
Tavegil is contraindicated during pregnancy, intolerance to clemastine, breastfeeding. The drug is not used in the treatment of MAO inhibitors, with bronchial asthma, diseases of the lower respiratory tract, in pediatrics. At pyloric stenosis, bladder neck obstruction, angle-closure glaucoma, prostate hyperplasia, heart disease, thyrotoxicosis, arterial hypertension Tavegil is used with caution. For children up to a year, the drug is prescribed in the form of solutions for injection, syrup. The tablet form of the drug can be taken after 6 years of age.
Nervous system: tremor of limbs, dizziness, increased drowsiness, fatigue, feeling tired, headaches, impaired coordination of movements, lethargy. In children, the stimulating effect of the drug on the nervous system is noted, manifested by convulsions, euphoric, excitement, anxiety, neuritis, paresthesiashysteria, insomnia.
Sensory organs: noise in ears, acute labyrinthitis, diplopia, disturbances in the work of the visual analyzer.
Digestive system: gastralgia, dyspeptic disorders, stool disorders, vomiting, loss of appetite, dry mouth.
urinary system: difficulty urinating, frequent urge.
Respiratory system: nasal congestion, disturbances and difficulty breathing, pressure behind the sternum, difficulty in sputum separation, thickening of the secretion of the bronchial tree.
The cardiovascular system: extrasystole, heart palpitations, drop in blood pressure.
Hematopoietic organs: agranulocytosis, thrombocytopenia, hemolytic anemia. Perhaps development bronchospasmanaphylactic shock, shortness of breath, photosensitization.
Instructions for use Tavegil (method and dosage)
Tavegil tablets, instructions for use
The tablet form is taken orally twice a day at a dosage of 1 mg. The maximum allowable daily amount of Tavegil is 6 mg. Children: 0.5 mg twice a day. For children from 1 to 6 years, the medicine is prescribed in the form of a syrup, 1 teaspoon. Under 1 year is not recommended to use the drug.
Instructions for use of Tavegil in ampoules
Intravenous and intramuscular administration of the drug is carried out 2 mg twice a day, children from 1 year to 12 years old are injected with 12.5 μg / kg 2 times. In order to prevent allergies, 2 mg of clemastine is given slowly once. The contents of the ampoule must be dissolved in 0.9% NaCl.
A medication in the form of an ointment is not performed.
In case of an overdose, nervous system excitation, anticholinergic effect are noted: disturbances in the digestive tract, blood flow to the skin of the face, fixed expansion of the pupils, dry mouth. Gastric lavage of 0.9% NaCl, salt laxatives, and asymptomatic therapy are recommended.
Tavegil enhances the effect of antipsychotics (antipsychotics), sleeping pills, sedatives, m-anticholinergic blockers. Concurrent use with MAO inhibitors.
Terms of sale
In a place inaccessible to children at a temperature of 15 to 30 degrees Celsius.
Up to five years.
According to the annotation, the injection contains ethanol. During the treatment period, it is recommended to exclude the intake of alcoholic beverages. Intraarterial administration of the drug is not allowed. For elderly patients, children require careful monitoring during the treatment period. Tavegil is canceled 72 hours before allergological tests to exclude results scarification allergy tests. Tavegil affects the driving of vehicles, the management of complex mechanisms.
Tavegil for children
Children under 1 year of age should not take the drug.
How to take from 1 to 6 years? The medicine is prescribed in the form of syrup for 1 teaspoon.
A solution from 1 year to 12 years is injected with injections of 12.5 μg / kg 2 times a day.
It is not recommended to use together with alcohol. The effects of alcohol and intoxication are amplified. The drug is an antihistamine of the first generation, against which doctors are extremely negative against taking alcohol. The simultaneous use of these substances is contraindicated.
Tavegil during pregnancy
You can not use Tavegil during pregnancy and breastfeeding.
Analogs of TavegilMatches for ATX Level 4 code:BenadrylClemastineDiphenhydramine
There are no direct analogues, however, drugs have a similar effect: Diphenhydramine, Suprastin, Pipolfen.
Reviews for Tavegil
Reviews about Tavegil tablets
They act quickly against allergic reactions, an inexpensive drug. However, there are strong side effects, in particular drowsiness, a hypnotic effect is very pronounced.
In general, they effectively cope with allergies. A pronounced hypnotic effect is also present. There are reviews that people felt sick after injections, pressure drops, dizzy, tachycardia appeared.
Tavegil price, where to buy
The price of Tavegil in tablets of 1 mg is 120 rubles for 10 pieces, and 175 rubles for 20 pieces.
How much are allergy pills in Ukraine? The cost, for example, in Kharkov is 90 UAH for a package of 20 pieces.
The price of Tavegil in ampoules of 2 ml is 185 rubles for 5 pieces.
Buying syrup in pharmacies is extremely difficult.
- Online Pharmacies in Russia
- Online pharmacies in UkraineUkraine
- Online pharmacies in Kazakhstan
- Tavegil Tab. 1mg n20Famar Italia S.p.A. 235 rub.order
- Tavegil solution in / in and / m 1mg / ml 2ml n5Nycomed Austria / Takeda Austria GmbH 353 rub.order
- Tavegil Tab. 1mg n10Famar Italy S.p.A.186 rub.order
- Tavegil (double) tablets 0,001g No. 20219 rub.order
- Tavegil (amp. 2ml No. 5) 346 rub.order
- Tavegil tablets 0.001g №10154 rub. Order
- Tavegil (tab. 0.001 g No. 10) 150 rub.
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- Tavegil 1 mg No. 10 tabletsFamar Italy S.p.A. / for Novartis180 rub.order
- Tavegil injection 1 mg / ml 2 ml n5 ampTakeda Austria GmbH 3999 rub.order
- Tavegil 2 mg 2 ml No. 5 solution for injection Takeda Austria GmbH, Austria97 UAH order
- Tavegil 1 mg No. 20 tablets Famar Іtalіya S.p.A. , Італія79 UAH to order
- Tavegil ampoule Tavegil solution d / in. 1 mg / ml amp. 2ml №5 Austria, Takeda Austria 104 UAH order
- Tavegil tablets Tavegil tablets. 1mg No. 20 Italy, Famar Italia 92 UAH order
- Tavegil 1 mg / ml 2 ml No. 5 solution for in amp. Takeda Austria GmbH. (Austria) 1 tenge
- Tavegil 1 mg No. 20 tablets Famar Italia S.p.A. (Italy) 1 tg.order