Medication

Nazol

Structure

In 1 ml spray contains: 0.5 mg oxymetazoline hydrochloride and auxiliary substances (macrogol, benzalkonium chloride, povidone, propylene glycol, sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate, edetate disodium dihydrate, purified water).

Release form

Spray for the nose 0.05% in a bottle of 15 and 30 ml.

Pharmachologic effect

Nazol is having local vasoconstrictor and decongestantact.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The active substance of the drug (oxymetazoline hydrochloride) has a pronounced adrenomimetic activity. The effect of this medication is to stimulate alpha adrenergic receptors smooth muscle vessels. Stimulation of these receptors is accompanied by a narrowing of blood vessels and a decrease in their permeability. Reducing blood flow eliminates edema mucous membrane and nasal breathing is facilitated.

Excipients of the drug moisturize the mucous membrane and eliminate its irritation. The vasoconstrictor effect appears after 10 minutes, and the decongestant effect persists for 10 hours.

Pharmacokinetics

After injection, it is rapidly absorbed from the nasal mucosa. The elimination half-life is 5-8 days. The drug is excreted in urine and feces.

Indications for use

Treatment allergic rhinitis, acute rhinitis at flu and respiratory diseases. Complex treatment middle otitis, eustachitis.

Elimination of swelling of the nasal mucosa during diagnostic procedures, before and after surgical interventions in this area.

Nasol can be used as monotherapy or with other drugs.

Contraindications

  • children under 6 years old;
  • increased individual sensitivity and intolerance to the components of the drug;
  • expressed atherosclerosis;
  • severe form arterial hypertension;
  • chronic rhinitis;
  • curvature of the septum of the nose;
  • diabetes;
  • hyperthyroidism;
  • glaucoma;
  • prostatic hypertrophy;
  • impaired renal function.

Side effects

Burning and tingling in the nose.

With prolonged use, a gradual weakening of the vasoconstrictor effect with the resumption of rhinitis.

Nazol, instructions for use (method and dosage)

Before using the medicine, you must thoroughly clean the nasal passages. Do not throw your head back when injected. For effective injection, the bottle is placed nebulizer up in the nasal passage. When inhaling through the nose, the bottle is sharply squeezed, making injection, while the other nasal passage must be closed. Then they inject into the second nasal passage. Nazol Spray is prescribed for adults and children over 12 years of age: 2 injections in both nostrils 2 times a day, observing an interval of 12 hours. Do not use the drug for more than 3 days. If there is no effect during this time, it is recommended to consult a doctor.

Children from 6 to 12 - 1 dose (1 injection) 2 times a day. In order to avoid side effects, the instructions for the use of Nazol should be strictly observed.

Overdose

Occurs when non-compliance with recommendations and uncontrolled prolonged use of the drug. Manifested heart rhythm disturbances, increased blood pressure, nausea, headache, drowsiness or insomnia, fatigue.

Interaction

The drug affects the absorption of local anesthetics, slowing it down, lengthens the effect of these drugs. With simultaneous use with other vasoconstrictor agents, the likelihood of side effects is high. Is celebrated increase in blood pressure with the appointment of Nazol and MAO blockers (Moclobemide, Pyrazidol), as well as tricyclic antidepressants.

Terms of sale

OTC vacation.

Storage conditions

Store in a dry place. Storage temperature not higher than 25 ° C.

Shelf life

Shelf life is 3 years.

Analogs

Matches for ATX Level 4 code:Ximelin EcoXimelinNazivinGalazolinLazorinNazivin Sensitive for childrenOtrivinNaphthyzineSanorinKnoxprayForLazolvan RenoAfrinRinorusEvkazolin AquaRinazolinInfluenza RinoFarmazolinXylometazolineNazol Advance

Nazivin, Nesopin, Oxymethazoline.

Reviews about Nazole

According to most patients, this is an effective, fast-acting drug that has a long-lasting effect (about 8 hours), which is very important during a night's sleep. Many note the effectiveness of the drug in allergic rhinitis, in which similar drugs do not give such an effect.

However, there are also negative reviews and they are associated with the appearance of adverse reactions of the drug. So, for example, an increase in blood pressure. It must be borne in mind that all vasoconstrictors, except for local action, also have a systemic effect on the vessels, in connection with which, strict adherence to the frequency of use of the drug during the day is necessary, and for people with hypertension, use Nazol, like any other vasoconstrictor, with extreme caution . Among the disadvantages of the drug, some patients also note the appearance of dryness of the nasal mucosa after prolonged use with vasomotor rhinitis. There are complaints that the spray is poorly sprayed, not injected deeply. Many are not satisfied with its value.

Nazol price, where to buy

The price of Nazol depends on the manufacturer and the volume of the bottle. You can buy in pharmacies in Moscow and other cities. The cost of the drug in 15 ml in a bottle ranges from 126 rubles. up to 201 rubles, and 30 ml each - from 215 rubles. up to 239 rub.

  • Online Pharmacies in Russia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in Kazakhstan

LuxPharma * special offer

  • Throside (Thioconazole) cream 1% 20g750 rub.order

ZdravCity

  • Nazol Spray 0.025mg / dose 10ml Institute de Angeli S.R.L. 164 rub.order
  • Nazol Advance Spray doses. 0.025mg / dose 10ml Institute de Angeli S.R.L. 203 rub.order
  • Nazol baby drops naz. 0.125% 10ml n1Institut de Angeli S.R.L. 216 rub.order
  • Nazol Kids Spray Naz. child 0.25% 10ml Institut de Angeli S.R.L. 177 rub.order

Pharmacy Dialog

  • Nazol (spray 0.025mg / dose 10ml) 157 rub.
  • Nazol Advance (spray 0.025mg / dose 10ml) 198 rub.
  • Nazol Baby (fl.cap. 0.125% 10ml) 217 ​​rub.order
  • Nazol Kids (spray 0.125% 10ml) 142 rub.

Eurofarm * 4% discount on the promotional code medside11

  • Nazol baby nasal drops 0.125% 10 ml Institut de Angeli S.R.L. 250 rub.order
  • Nazol nasal spray 0.025 mg / dose 10 ml (150 doses) De Angeli Institute S.R.L. / Bayer189 rub.order
  • Nazol Advance Nasal Spray 0.025 mg / dose 10 ml (150 doses) Institute de Angeli S.R.L. (Bayer230 rub.order
  • Nazol Kids Nasal Spray 0.125 mg / dose 10 ml Institut de Andgeli S.R.L. 155 rubles order
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Pharmacy24

  • Nazol Baby 0.125% 10 ml drops Istituto de Angeli S.r.l., Italiya57 UAH order
  • Nazol Advance 0.05% 10 ml spray Istituto de Angeli S.r.l., Italy 63 UAH.order
  • Nazol 0.05% 10 ml spray Istuto de Angeli S.r.l., Italy 50 UAH.order
  • Nazol Kids 0.25% 10 ml spray Istituto de Angeli S.r.l., Italy66 UAH.order

Pani Pharmacy

  • Nazol Baby Liquid Nazol Baby Drops Naz. 0.125% 10ml Italy, Instituto de Angeli 64 UAH order
  • Nazol liquid Nazol spray nasal spray. 0.05% fl. 10ml Italy, Instituto de Angeli 64 UAH.order
  • Nazol Kids Liquid Nazol Kids Spray 10ml Italy, Instituto de Angeli 82 UAH order
  • Nazol Advance Liquid Nazol Advance Naz. spray 10ml Italy, Instituto de Angeli 75 UAH order
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BIOSPHERE

  • Nazol Advance 15ml Spray named Sagmel, Inc. (Italy) 690 tg.order
  • Nazol Advance 10 ml spray named after Instituto De Angeli S.r.l. (Italy) 980 tg.order
  • Nazol 0.05% 10 ml spray named Institute Institute de Angeli S.R.L. (Italy) 940 tg.order
  • Nazol Kids 10 ml spray n.z. flak. Dozers. Instituto De Angeli S.R.L. (Italy) 835 tg.order
  • Nazol Baby 0.125% 10 ml drops named after Instituto De Angeli S.r.l. (Italy) 790 tg.order
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