The drug contains an active substance human immunoglobulin anticytomegalovirusas well as glycine as a stabilizer.
Available in the form of a solution, which is contained in ampoules, in cartons of cardboard contains 10 ampoules.
Immunoglobulin anticytomegalovirus - This is a biological fraction with pronounced immunological activity, which is released from human plasma. The active basis of the drug is specific to cytomegalovirusantibodies, namely immunoglobulin G.
Due to the virus-neutralizing effect, the drug has a specific activity. In addition, it provides an immunomodulatory effect, since the immunoglobulin G drug acts on the body's immune system. As a result, there is an increase in immunity and an increase in nonspecific resistance.
Pharmacokinetics and pharmacodynamics
No data available.
Indications for use
Anticytomegalovirus immunoglobulin is prescribed for therapy cytomegalovirus infection with different clinical manifestations, both in children and in adults. In particular, the drug is indicated if a person has such diseases and conditions:
- Cytomegalovirus infection in pregnant subject to a complicated history, the drug is prescribed in order to prevent pregnancy disorders.
- Cytomegalovirus infection in non-pregnant women, subject to a history of complications, in order to prevent those disorders that may occur during pregnancy afterwards.
- Cytomegalovirus infection in pregnant women, provided there is no history of complications, in order to prevent complications.
- Manifestations of cytomegalovirus infection in children of the first years of life and in newborn babies who were born infected or have clinical signs of infection in women.
- Cytomegalovirus infection in adult patients with CNS lesions.
Do not administer the drug to people with a history of severe allergic manifestations after the introduction of protein blood products.
After the patient is administered Immunoglobulin anticytomegalovirus, in some rare cases, may be noted manifestation of hyperemia as a local reaction, as well as a slight increase in body temperature in the first day after the introduction of the solution.
People with altered reactivity may experience allergic reactions all kinds of. Very rarely development is possible anaphylactic shock. Therefore, after receiving the injection, the patient should remain under the supervision of a doctor for another 30 minutes.
Instructions for use (Method and dosage)
Anti-cytomegalovirus immunoglobulin is administered only intramuscularly, intravenous administration is prohibited.
In order to treat a cytomegalovirus infection with a burdened obstetric history, both in pregnant women and non-pregnant women, it is necessary to enter the contents of one ampoule 4-5 times. Moreover, the interval between administrations is from 3 to 5 days.
In order to treat cytomegalovirus infection in people suffering from central nervous system lesions, the contents of 3 ampoules are administered 5 times, while the interval between injections is 2 days.
In the treatment of cytomegalovirus infection in newborns, the drug should be administered three times a day at a dose of 0.5 ml per 1 kg of body weight, while the interval between drug injections should be 2-3 days.
In the treatment of cytomegalovirus infection in children of the first years of life, the contents of 1 ampoule should be administered 4-5 times, while the interval between administrations is 5 days.
No data on overdose.
The feasibility of combined immunoglobulin and Foscarneta or Ganciclovir.
You can not enter together with any of the drugs in one volume.
Terms of sale
In pharmacies, it is sold by prescription.
Store and transport the medicine at a temperature of 2-8 ° C. The solution should not be frozen.
You can store 2 years.
People suffering allergies, or with a history of allergic diseases, should be on the day they were given immunoglobulin, and take the next three days antihistamines. People who suffer from immunopathological systemic diseases can be given immunoglobulin only with the necessary treatment.
After a course of treatment with the drug, the patient can be vaccinated with live vaccines only 2-3 months after the completion of such treatment.
If indicated, it is used to treat newborns and children.
During pregnancy and lactation
Clinical experience indicates that the drug does not have a negative effect on the fetus and on the condition of the mother. Since immunoglobulin passes into breast milk, protective antibodies can be passed from mother to newborn.
Patients rarely leave reviews of Immunoglobulin anticytomegalovirus, however, their effectiveness is noted in them, especially as part of complex treatment.
Price, where to buy
The price of a package of Immunoglobulin anticytomegalovirus (10 ampoules) is from 7400 rubles.