The composition of this medicine is included as the main substance. human immunoglobulin antistaphylococcal (anti-alfastavafilolizin), as additional substances - glycine, sodium chloride.
It is produced in the form of a solution that is administered intramuscularly, the solution is packaged in ampoules, and in a pack of cardboard - 10 ampoules.
Human anti-staphylococcal immunoglobulin is a protein fraction with immunological activity that is obtained from human plasma. It contains antibodies to staphylococcal exotoxin. The preparation contains from 9 to 11% protein. Also, under the influence of this medicine, the nonspecific resistance of the body increases.
Pharmacokinetics and pharmacodynamics
Highest concentration antibodies in the blood is observed 24 hours after administration of the drug. The elimination half-life from an organism equals four to five weeks.
Indications for use
Immunoglobulin antistaphylococcal assigned to people who have been diagnosed with a disease of staphylococcal etiology. It is used to treat adults and children.
You can not use the Human immunoglobulin antistaphylococcal in the following cases:
- provided that the patient has a history of severe allergic reactions after the introduction of blood products;
- with severe sepsis in people who have a history of anaphylactic shock with the introduction of blood products;
- at allergic diseases or if there is a history of serious allergic reactions on the day the immunoglobulins were administered, and for eight days after the injection was given. In this case, you can take Immunoglobulin against a background of antihistamines;
- people with systemic immunopathological diseases should receive the drug only with appropriate treatment.
In most cases, after the administration of this drug, a person does not manifest adverse reactions. Very rarely there is a rise in body temperature, local reactions in the place where the solution was injected.
In patients who have an altered reactivity, a manifestation of allergic reactions. Development is very rare. anaphylactic shock. Therefore, each person who received an injection of Immunoglobulin should be under the supervision of specialists for half an hour. In this case, the doctor must have access to funds for anti-shock treatment.
Instructions for antistaphylococcal Immunoglobulin (Method and dosage)
The solution is injected intramuscularly in the buttocks or on the outer surface of the thigh. Before you enter the tool, you need to withstand the ampoule at room temperature for two hours.
It is necessary to strictly observe the requirements of aseptic and antiseptic, opening the ampoules and performing the introduction. Staphylococcal Immunoglobulin is desirable to draw into a syringe using a needle with a wide clearance. Do not store the solution in an opened ampoule. The dosage and frequency of administration of the solution depends on the characteristics of the course of the disease. If the patient has been diagnosed generalized staph infection, then a single dose should be determined based on 5 ME of the drug per 1 kg of patient weight. Children under 5 years old should receive a single dose of at least 100 ME.
If the patient is noted localized disease, a single dose of at least 100 ME should be administered to him.
From 3 to 5 injections are prescribed for the course of treatment, they are carried out daily or every other day, depending on the doctor's prescription.
You can not use Immunoglobulin with an expired shelf life, damaged ampoules, a solution with altered physical properties.
The injection is recorded in a special form.
There is no data on an overdose of funds.
The drug is compatible with other drugs, it can be taken simultaneously with antibioticsuse in complex therapy.
Immunoglobulin antistaphylococcal can be administered no earlier than three months after the patient has been immunized with live viral vaccines. The drug does not affect the effectiveness of other vaccines.
After receiving the drug from the patient, the results of serological reactions may change. The result in this case may be false positive.
Terms of sale
Antistaphylococcal immunoglobulin can be purchased only by prescription.
When storing or transporting the product, the appropriate temperature regime must be observed - from 2 to 8 ° C. Do not freeze the drug.
Shelf life is 2 years.
People who celebrate allergic diseases, or there is a tendency to develop allergic reactions, should be on the day of receiving Immunoglobulin and take the next eight days antihistamines. With an exacerbation of allergic processes, you can enter the drug only if there is an appropriate conclusion from an allergist.
After the introduction of the drug, psychomotor disturbances are not observed, respectively, driving vehicles and working with complex mechanisms are allowed.
According to the indications, it is prescribed for the treatment of children in the appropriate dosage. Children under 5 years old should receive a single dose of at least 100 ME.
During pregnancy and lactation
Can be taken during of pregnancyas well as breastfeedingonly in the presence of vital indications. In this case, the specialist must evaluate the alleged harm and benefit. It should be noted that the active substance passes into milk, therefore protective antibodies can enter the body of a newborn.
Reviews on human antistaphylococcal Immunoglobulin
Reviews of those people who took staphylococcal Immunoglobulin indicate a different reaction of the body. It is noted that after taking the drug, a pronounced effect appeared. However, there are also reviews that after taking the remedy there was no noticeable improvement in health status.
Price of immunoglobulin antistaphylococcal, where to buy
The price of the drug averages 9600 rubles per 10 ampoules. Where to buy staphylococcal Immunoglobulin can be found at the nearest medical institution.