The medicine contains as an active substance acetazolamide.
Additional components: potato starch, sodium starch glycolate, talc.
Available in the form of round flat tablets in white.
Diuretic and decongestant means.
Pharmacodynamics and pharmacokinetics
Diacarb tablets are diuretic. Them diureticaction related to inhibition of carbonic anhydraseinvolved in the exchange of carbonic acid. Inhibition of this enzyme occurs in kidney tissue. As a result of this, the degree of repeated absorption at blood from urine sodium and bicarbonate ions.
This drug also helps with pulmonary heart disease, which can occur with some lung diseases, for example, with emphysema. In addition, it can be used with excessive intracranial pressure. is he inhibits carbonic anhydrase brain, which leads to a decrease in the formation of cerebrospinal fluid and intracranial pressure. Accordingly, the symptoms associated with it are removed, for example, headache.
Once in the body, this drug is also inhibits carbonic anhydrase ciliary body, which causes its use in acute attacks glaucoma. Its action causes a decrease in the secretion of aqueous humor and normalizes its outflow.
In general, tablets are widely used for water and sodium retention in the body, as well as for prevention edema different genesis. Thus, they can be used in the treatment of many diseases. Helping in the normalization of water-salt metabolism, they do not upset the acid-base balance. Duration of action is up to 12 hours.
After oralapplication in a dosage of 500 mg, the maximum concentration of the drug in plasma is reached after 2 hours. Its action is characterized by a high degree of binding to plasma proteins. The active substance crosses the placental barrier.
The medicine is excreted through the kidneys unchanged, mainly during the day.
Indications for use Diakarba
Only as diuretic Diacarb is rarely used, since there are more effective drugs of this series. But it is often used for diseases not related to the genitourinary system, if there are appropriate indications for the use of Diakarb.
It is not recommended that you take these pills on your own, without consulting a doctor, from which they will help and how they will act, only a specialist knows.
Indications for use of diacarb may be as follows:
- Edema syndrome (moderate or mild severity);
- Epilepsy (as one of the means of combined treatment);
- Mountain sickness;
- Some pulmonary diseases when a lot of carbon dioxide and bicarbonates accumulate in the blood.
You can not use this tool with hypersensitivity to its components, liver failure, acidosis, Addison's disease, diabetes, breastfeeding, of pregnancy, acute renal failure, hypokalemia, hypocorticism, uremia.
With caution, it is prescribed when edema hepatic and renal origin, as well as the use of high doses of acetylsalicylic acid.
Side effects when taking the drug may be as follows: hypokalemia, cramps, paresthesia, anorexia, itching, hives, muscle weakness, hyperemia skin, sensation of tinnitus, metabolic acidosis myopia.
With prolonged therapy, nephrolithiasis, glucosuria, leukopeniadisorientation drowsinessvomiting allergy, hematuria, hemolytic anemia, agranulocytosis, impaired touch, nausea, diarrhea.
If side effects occur while taking this remedy, you should immediately consult a doctor.
Instructions for use Diakarba (Method and dosage)
For those who have been prescribed Diakarb tablets, the instructions for use report that the dosage regimen may be different depending on the disease, the characteristics of the body and the age of the patient.
When edematous syndrome The initial daily dosage is 250-375 mg. You need to take the drug once a day. Maximum diuretic the effect appears after 1-2 days of administration. Then it is advisable to take a break for 24 hours. When taking the medicine, the instructions for use of Diakarba advise along with the therapy of circulatory failure, replenish the level of potassium and follow a diet limited in salt intake.
At open angle glaucomathe medicine is taken several times a day. Dose - 250 mg. When secondary glaucoma appoint 250 mg every 4 hours. Children are prescribed 10-15 mg per 1 kg of body weight per day. The daily dosage must be divided into several doses.
Tablets in a dosage of 500-1000 mg / day are recommended to be taken before climbing a mountain in 1-2 days. If symptoms mountain sickness still appear, it is necessary to continue therapy for two days.
At epilepsy adult patients are given 250-500 mg of the drug per day. The course is designed for 3 days. Then you need to take a break. In turn, the instruction for the use of Diakarba for children provides the following daily dosages, depending on age:
- 4-12 months - 50 mg;
- 2-3 years - 50-125 mg;
- 4-18 years old - 125-500 mg.
When combined with anticonvulsant preparations, the initial daily dosage is 250 mg. If required, it can be increased. But children should not take a daily dose in excess of 750 mg.
For any indication, if a dose was missed, the next dose should not be increased.
In the case of the use of the drug in high doses, an increase in adverse reactions is likely. The treatment is symptomatic.
When combined with diacarb antiepileptic Reinforcement possible osteomalacia. A interaction with diuretics and Theophyllineleads to a significant increase diureticactions. But this does not apply acid-forming diuretics. In this case diuretic action, on the contrary, is reduced.
In addition, the tool increases the likelihood of a toxic effect. salicylates, Carbamazepine, non-depolarizing muscle relaxantsdigitalis medicine Ephedrine.
Terms of sale
This drug is sold only by prescription.
Keep the medicine in a dry place inaccessible to children at temperatures up to 25 ° C. Tablets should be protected from exposure to sunlight.
Analogs of DiakarbaMatches for ATX Level 4 code:DorzoptAzoptTrusopt
Analogues of Diakarba are currently virtually absent. In some pharmacies, you can only find a remedy called Acetazolamide. In fact, this is another name for the same medicine. Other analogues of the drug are not known.
Diacarb for children
When hydrocephalus or hypertensive hydrocephalic syndrome Often prescribed Diacarb for children. It regulates the amount of cerebrospinal fluid. In addition, Diacarb for children may be prescribed when glaucoma or epilepsy.
It is prescribed with a prescription, since the use of this medication requires monitoring by a specialist. It is best to use it in a hospital, when monitoring the condition of the child can be carried out at the proper quality level.
However, today there are frequent cases when, with a mild condition, a neurologist can prescribe taking the drug at home.
Parents should keep in mind that this drug can provoke serious adverse reactions. It is necessary to monitor the condition of the child, as convulsions, nausea, muscle weakness, hypokalemia, vomiting, allergic reactions. And with prolonged use in children, a decrease in the number is sometimes observed white blood cellsand hemolytic anemia. Often, if necessary, a long course can also be prescribed Asparkamto reduce the elimination of potassium from the body.
Usually, the doctor selects the dosage himself after examining the child and obtaining the results of the tests. According to the instructions, the minimum dosage is 50 mg per day. The daily dose is given to the child in 1-2 doses.
Diacarb for newborns
Children up to a year may be prescribed this drug with epilepsy. In addition, Diacarb for newborns is used for excessive enlargement or divergence of skull sutures. It helps reduce cerebrospinal fluid.
For newborns, this remedy is prescribed by a doctor. Reception of Diakarb requires careful monitoring by a specialist.
The best option is to monitor the baby in a hospital throughout the course. However, often this drug is given at home. In this case, the specialist is obliged to warn parents of possible adverse reactions and stipulate the exact timing of admission (no more than 5 days). Upon completion of the course, you must once again pass the appropriate tests.
In pregnancy (and lactation)
This tool should not be taken with of pregnancy. If you need to take the drug during lactation, breast-feeding should be discontinued.
Reviews about Diakarbe
Opinions about the drug can be found very different. Some reviews of Diakarba report that the medicine helped, while in others, people complain of side effects. In the latter case, convulsions and muscle weakness. But in general, positive reviews of Diakarbe are still more common.
Some forums are also interested in whether this remedy can be used during pregnancy. Experts give an unambiguously negative answer to this question. Pregnant women are not prescribed the drug.
Price Diakarba where to buy
Diacarb tablets are reasonably priced. They can be found in many pharmacies. The price of Diakarb is about 210 rubles. This tool is also sold in Ukraine. The price of Diacarb in tablets of 250 mg (30 pieces per pack) averages 140 hryvnias.
- Online Pharmacies in Russia
- Online pharmacies in UkraineUkraine
- Online pharmacies in Kazakhstan
- Diacarb tablets 250mg No. 30 AKRIKHINOAO AKRIKHIN242 rub.order
- Diacarb tablets 250mg №30280 rub.order
- Diacarb 250 mg N30 tablets Pharmaceutical factory "POLFARMA" SA, Poland / Medana Pharma Akcіonerne Partnership, Poland 261 UAH order
- Diacarb tablets Diacarb tablets 250mg No. 30 Poland, Polpharma 246 UAH order
- Diacarb 250 mg No. 30 tablets of Polpharma (Poland) 1 tg.