Medication

Celebrex

Structure

One capsule contains 200 milligrams. celecoxib.

As auxiliary components, sodium croscarmellose, povidone K30, sodium lauryl sulfate, lactose monohydrate and magnesium stearate are present. The shell consists of titanium dioxide and gelatin.

Release form

The drug is available in the form of gelatin capsules, the contents of the capsules is white.

Pharmachologic effect

Celecoxib inhibits the activity of COX2 and also slightly suppresses COX1. It has anti-inflammatory, antipyretic and painkilleraction, reduces the risk of colon cancer.

The use of this drug is much safer than the use of other NSAIDs, since it practically does not cause a risk of gastroduodenal ulcers, and also does not violate the natural processes associated with class E1 prostaglandins in the stomach and intestines.

Pharmacodynamics and pharmacokinetics

The drug is very well absorbed on an empty stomach from the digestive tract. The maximum concentration is reached in about two or three hours. Eating fatty foods slows the absorption of the drug for four hours. It is excreted 99 percent through the liver, can penetrate the BBB.

Indications for use

What are Celebrex tablets from? Indications for use of the drug are as follows:

  • acute back pain;
  • algodismenorea;
  • arthritis (osteoarthritis, rheumatoid arthritis), spondylitis;
  • complex therapy of patients with familial adenomatous polyposis.

Contraindications

The drug should not be taken with:

  • condition after surgery for coronary artery bypass grafting;
  • allergic reactions taking acetylsalicylic acid or other NSAIDs;
    intolerance to sulfonamides or components of the drug;
  • period lactation;
  • of pregnancy;
  • heavy renal failure;
  • heavy liver failure;
  • severe cerebrovascular diseases;
  • peripheral artery disease;
  • heart failure;
  • gastrointestinal bleeding;
  • aggravated peptic ulcer;
  • hypersensitivity to the components of the drug;
  • under the age of 18 years.

Side effects

Often observed:

  • skin rash and itching;
  • upper respiratory tract infections sinusitis, rhinitis, pharyngitis, cough and bronchitis;
  • urinary tract infections;
  • insomniaincreased muscle tone, dizziness;
  • dental diseases flatulence, dyspepsia, diarrheaabdominal pain;
  • peripheral edema;
  • flu-like syndrome, exacerbation allergies.

Infrequently observed:

  • hives, alopecia;
  • drowsiness, anxiety;
  • vomiting;
  • blurred vision noise in ears;
  • tachycardia, heartbeat, hot flashes, arrhythmia, increased blood pressure, worsening with arterial hypertension;
  • thrombocytopenia, ecchymoses, anemia.

Rarely observed:

  • confusion of consciousness;
  • bullous rashes, angioedema;
  • increased activity of liver enzymes, intestinal perforation, ulceration of the esophagus;
  • duodenal ulcer;
  • myocardial infarction, ischemic strokeoccurrence of stagnant heart failure.

Celebrex capsules, instructions for use (Method and dosage)

According to the instructions for the use of Celebrex, the drug must be taken 200 milligrams twice a day. It is necessary to select the minimum effective dose and a short course of treatment.

With familial adenomatous polyposis the drug is taken as an additional tool at 400 milligrams twice a day.

In acute pain - initially from 400 to 600 milligrams per day, then 200 milligrams twice a day.

With ankylosing spondylitis - 100 milligrams twice a day. The maximum is 400 milligrams per day.

At rheumatoid arthritis - from 200 to 400 milligrams per day, the dose is divided into two doses. The maximum dose is 800 milligrams per day.

If the patient has a decrease in liver function, the dose must be reduced by half.

Overdose

In case of an overdose, it is necessary to take measures to remove the drug and conduct symptomatic therapy.

Interaction

Do not use this drug simultaneously with other NSAIDs that do not contain acetylsalicylic acid.

Since the drug does not affect the antiplatelet effect acetylsalicylic acidIt is not considered as a substitute for the prevention of cardiovascular disease.

Do not interact with Tolbutamide, Phenytoin, Glibenclamide, Methotrexate, Omeprazole and antacids. With the simultaneous administration of celecoxib and lithium, an increase in the concentration of the second in plasma by 17 percent is noted.

Terms of sale

The drug can be purchased only with a prescription.

Storage conditions

Store the medicine in a dry place at a temperature of 15 to 30 degrees.

Shelf life

The shelf life of the drug is three years.

Analogs Celebrex

Matches for ATX Level 4 code:DenebolCelecoxibArcoxiaRancelex

Analogues of the drug:

  • Artoxib;
  • Zitsel;
  • Rancelex;
  • Revmoxib;
  • Celecoxib.

The price of Celebrex analogues is a little cheaper.

Reviews about Celebrex

According to reviews of Celebrex on the forums, the drug is very effective, but also the reviews of patients indicate numerous side effects of this drug.

Celebrex price where to buy

The price of Celebrex 200 milligrams in Russia is an average of 400 rubles (10 capsules).

In Ukraine, the cost of the drug is an average of 220 hryvnia.

The price of Celebrex tablets for 3 blisters per pack is in the range of 1000-1100 rubles.

  • Online Pharmacies in Russia
  • Online pharmacies in UkraineUkraine

ZdravCity

  • Celebrex caps. 400mg n1 + 200mg n5Pfizer Pharmaceuticals ElElSi219 rub.order
  • Celebrex caps. 100mg n10Pfizer Pharmasyut. ELC / R-Pharm Germany GmbH586 rub.order
  • Celebrex caps. 200mg n30Pfizer Pharmasyut. ELC / R-Pharm Germany GmbH1457 rub.order
  • Celebrex caps. 200mg n10Pfizer Pharmasyut. ElElSi. / R-Farm Germany GmbH545 rub.order

Pharmacy Dialog

  • Celebrex (caps. 200mg No. 10) 511 rub.order
  • Celebrex (caps. 100mg No. 10) 516 rub.order
  • Celebrex capsules 200mg №301103 rub.order
  • Celebrex capsules 400mg No. 1 + 200mg No. 5185 rub.order

Eurofarm * 4% discount on the promotional code medside11

  • Celebrex combined 400 mg No. 1 caps + 200 mg No. 5 capsPfizer Pharmaceuticals ElElSi / R-230 rub.order
  • Celebrex 200 mg n30 capsPfizer Pharmaceuticals ElElSi / R-1390 rub.order
  • Celebrex 200 mg n10 capsulesPfizer Pharmaceuticals ElElSi / R-550 rub.order
  • Celebrex 100 mg n10 capsPfizer Pharmaceuticals ElElSi / R-640 rub.order
show more

Pharmacy24

  • Celebrex 200 mg No. 20 capsules R-Pharm Germani GmbH, Nimechchina363 UAH.order

Pani Pharmacy

  • Celebrex capsule Celebrex capsules 200mg No. 20 Germany, R-Pharm Germany GmbH 388 UAH order
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