Medication

Pyridoxine

Structure

One injection vial contains the active ingredient: pyridoxine hydrochloride 10 or 50 mg.

Additional substance: water for injection.

The tablet includes 2, 5 or 10 mg pyridoxine hydrochloride.

Release form

Pyridoxine hydrochloride in the form of a solution for injection, packaged in ampoules of 1 ml, 10 ampoules in a box.

Tablets are packed in a jar of 50 pieces.

Pharmachologic effect

The drug has an effect, making up for the deficit Vitamin B6

Pharmacodynamics and pharmacokinetics

As known, vitamin b6 It is an indispensable participant in metabolic processes, normalizes and supports the activity of the nervous system. The phosphorylated form of pyridoxine is a coenzyme of a significant number of enzymes that affect the non-oxidative exchange of amino acids, for example, decarboxylation or transamination. This component is necessary for metabolic processes. tryptophan, cysteine, glutamine, methionine and other amino acids. It is important for exchange histamine and to normalize lipid metabolism.

The metabolism of the main substance occurs in the liver, resulting in the formation of pharmacologically active metabolites: pyridoxalphosphate and pyridoxamine phosphate. The components are distributed mainly in the muscle tissues, as well as in the liver and nervous system. The penetration of the drug into breast milk and through the placenta was noted. The substance is excreted with the kidneys, part with bile.

Indications for use

The drug is used to treat and prevent vitamin B6 deficiency in:

  • B6-hypovitaminosis;
  • toxicosis of pregnant women;
  • sideroblastic anemia;
  • leukopenia;
  • diseases of the nervous system;
  • sea ​​and air sickness;
  • atherosclerosis;
  • diabetes mellitus;
  • dermatitis;
  • herpes zoster;
  • neurodermatitis;
  • psoriasis
  • exudative diathesis and so on.

Contraindications

It is not recommended to take the drug with sensitivity or intolerancePyridoxine.

Special instructions

Caution is required when prescribing this drug to patients suffering from peptic ulcer and 12 duodenal ulcer, cardiac ischemia.

Taking high doses of pyridoxine with severe liver damage can worsen its function.

Side effects

During treatment, development is possible allergic reactionshypersecretion of hydrochloric acid.

Instructions for use Pyridoxine (Method and dosage)

Pyridoxine tablets are recommended for oral use for treatment hypovitaminosis. For adult patients, a dose of 80 mg is prescribed, to be taken 4 times a day.

Vitamins in ampoules, like Pyridoxine Vial, instructions for use indicate use in a daily dosage of 50-150 mg. Subcutaneous, intramuscular or intravenous administration is allowed. The duration of therapy is determined by the severity and type of violation. In the prevention of vitamin B6 deficiency, about 40 mg is prescribed per day.

Overdose

In clinical practice, cases of overdose have not been established.

Interaction

Concomitant use with isoniazid, cycloserine, penicillamine reduces the effectiveness of pyridoxine. Pharmaceutical incompatibility of vitamin B6 with B1 and B12 was noted. This drug significantly reduces antiparkinsonian activity. levodopa.

Combination with ghormonal contraceptives able to increase the concentration of pyridoxine in the blood plasma. Application with phenytoin and phenobarbital can reduce the concentration in the blood plasma of these components.

Terms of sale

It is allowed to dispense the drug without a prescription, but it should not be used alone.

Storage conditions

The medicine should be stored in a dry, dark, cool place, protected from children.

Shelf life

3 years.

Analogs

Matches for ATX Level 4 code:MedobiotinCalcium PantothenateVolvitNicotinamideAlpha tocopherol acetateBiotin ComplexRiboflavinPyridoxine HydrochlorideVitrum Vitamin E

Pyridoxine is a vitamin that is included in many combination preparations, for example: Magne Wb, Pernexin Elixir, Hepasteril-A, Hepasteril-B, Lipostabil, Essential.

The analogues of the drug are: Vitamin B6, Pyridobene, Pyradoxine, Adermin, Betsilan, Pyrivitol, Bedoxin, Benadon, Hexabetin, Hexabion, Hexavibexand others.

Combination Benfotiamine + Pyridoxine is a fat soluble analogue of vitamin B1 or thiamine. This combination normalizes the functions of the nervous system, taking part in carbohydrate metabolism, making up for vitamin B1 deficiency.

Alcohol

Excessive alcohol consumption reduces absorption. vitamin b6, increasing the body's need for it.

Pyridoxine for hair

Vitamin masks prepared at home are very popular. Pyridoxine for hair is often used for this purpose. It is known that this substance has a positive effect on hair growth, normalizes blood circulation.

To make a hair mask of medium length, use Pyridoxine Vial in ampoules - about 4-5 pieces.

You need to mix a spoonful of castor, olive and burdock oils. Heat this mixture in a water bath, add a solution Pyridoxine Vial and any other essential oils that suit your hair type. Mix well and apply to hair. You can put on a hat and stand for 30-40 minutes. Then wash your hair, rinse well with cool water. Practice shows that such a tool makes hair not only shiny and silky, but healthy and strong.

Reviews on Pyridoxine

Medical sites and forums in most cases contain positive reviews about pyridoxine. This drug is prescribed to many patients in the complex treatment of a variety of disorders, for example: hypovitaminosis B6, leukopenia, atherosclerosis, diabetes mellitus, herpes zoster, psoriasis, neurodermatitis and so on. Almost always, this vitamin significantly speeds up the healing effect.

However, some users ask: Pyridoxine - what is it? And when they learn that this is the name of vitamin B6, they are very surprised. As you know, pyridoxine helps well with toxicosis of pregnant women, eliminates the symptoms of air and sea sickness. But the fact that this substance is used in combination therapy of diseases of the central nervous system, not many know.

It should be noted that often patients do not use the drug in ampoules, but its tablet form.

Among the many positive reviews there are reports of the development of negative effects. In some patients, while taking this medication, the acidity of the gastric contents increased, which caused severe pain in patients with gastritis. However, experts argue that adhering to dosing and taking into account contraindications - ulcers and stomach diseases, will not lead to the development of side effects, since the drug is well tolerated. In rare cases, allergic reactions develop, but, as a rule, all symptoms are eliminated after discontinuation of the drug.

Pyridoxine price, where to buy

For pyridoxine tablets, the price varies between 40-60 rubles.

The price of pyridoxine in ampoules is 20-35 rubles.

  • Online Pharmacies in Russia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in Kazakhstan

ZdravCity

  • Pyridoxine (Vit B6) tab. 10mg n50Ozone LLC 52 rub.order
  • Pyridoxine (Vit B6) solution d / in. 5% 1ml №10 Borisov ZavodBorisovsk Zavod34 rub.order

Pharmacy Dialog

  • Vitamin B6 (pyridoxine g / x) (amp. 5% 1ml No. 10) 29 rub. Order
  • Vitamin B6 (pyridoxine g / x) (tab. 10 mg No. 50) 48 rub. Order
  • Vitamin B6 (pyridoxine g / x) (tab. 10mg No. 50) 47 rub. Order
  • Vitamin B6 (pyridoxine g / x) (amp. 5% 1ml №10) 28 rub. Order
  • Vitamin B6 (pyridoxine g / x) (amp. 5% 1ml №10) 26 rub. Order

Eurofarm * 4% discount on the promotional code medside11

  • Pyridoxine hydrochloride 10 mg n50 tableOzone LLC 50 rub.order
  • Pyridoxine hydrochloride injection 5% 1 ml n10 ampOAO "Yerevan HFF" 30 rub. Order
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Pharmacy24

  • Pyridoxine-Darnitsa 5% 1 ml No. 10 injection for 30 UAH order
  • Pyridoxine hydrochloride (Vitamin B6) 50 mg / ml 1 ml N10 injection for AT Lekhim-Kharkiv, Ukraine27 UAH order

Pani Pharmacy

  • Pyridoxine g / x rr d / in. 5% amp. 1ml №10 21 UAH to order
  • Pyridoxine solution d / in 50mg / ml amp. 1ml №10 Ukraine, Lekhim-Kharkov CJSC 25 UAH order
  • Pyridoxine g / x rr d / in. 5% amp. 1ml №10 Ukraine, Health LLC 26 UAH order
  • Pyridoxine g / x rr d / in. 5% amp. 1ml №10 Ukraine, Darnitsa PrJSC 36 UAH order
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BIOSPHERE

  • Pyridoxine hydrochloride 5% / 1 ml No. 10 solution for in. Amp. Borisov ZMP (Belarus) 270 tg.order
  • Pyridoxine hydrochloride 50 mg / ml No. 10 solution for in amp. Novosibkhimpharm OJSC (Russia) 250 tg.order
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