1 gram of cream, spray and dermgel (gel) of the drug Lamicon includes 10 mg terbinafineas an active ingredient.

Additional ingredients of the cream: soft white paraffin, phenylethyl and cetostearyl alcohol, sodium hydroxide, mineral oil, macrogol cetostearyl ether 20, poloxamer 407, propylene glycol, purified water.

Additional spray ingredients: propylene glycol, benzoic acid, macrogol cetostearyl ether 20, disodium edetate, poloxamer 407, water for injection.

Dermgel additional ingredients: gasoline alcohol, butylhydroxytoluene, sorbitan laurate, isopropyl myristate, polysorbate 20, ethanol 96%, sodium hydroxide, carbomer 974P, purified water.

1 tablet of Lamicon includes 250 mg terbinafineas an active ingredient.

Additional tablet ingredients: sodium starch glycolate, microcrystalline cellulose, anhydrous colloidal silicon dioxide, corn starch, magnesium stearate, hydroxypropyl methyl cellulose.

Release form

The drug Lamicon is made by Farmak company in the form of a cream of 15 grams, a spray of 25 grams, a gel of 15 and 30 grams and tablets of 14 or 28 pieces in the first package.

Pharmachologic effect


Pharmacodynamics and pharmacokinetics

Antifungal substance terbinafineis an alylamineexhibiting an active effect on a rather large number mushroom strains. Fungicidal act terbinafine, in adequate concentration, is distributed to mold fungi, dermatophytes, as well as some dimorphic fungi. In relation to yeast fungi, depending on their type, terbinafine exhibits fungicidal or fungistatic efficacy.

The mechanism of action of Lamicon lies in specific inhibition, in the membrane of fungal cells, an early stage sterol biosynthesis. The consequence of this effect is intracellular cumulation squaleneand ergosterol deficiency, which leads to the destruction of fungal cells.

Act terbinafinemanifested through the process of oppression, in the membranes of fungal cells,Squalene Epoxidase Enzymesystem related cytochrome P450. Lamicon does not have an effect on the effects of other drugs, as well as on the metabolism of hormones. For external (local) use terbinafine absorption It is less than 5% of the applied dose, and therefore, its systemic exposure is negligible.

When applied externally, Lamicon is absorbed in very small quantities, begins to act almost immediately and remains effective for a short time, about 7-14 days. The fungicidal effect of terbinafine, due to the preservation of its desired concentration in the stratum corneum epidermisreceived during treatment, continues for 7 days after the withdrawal of the external funds.

When taking Lamicon tablets internally, terbinafineaccumulates in the nails, hair, and skin, in concentrations that ensure its fungicidal effects. The absorption of the drug in the form of tablets is about 70%, with absolute bioavailabilityat about 50%.

After taking one 250 mg tablet, after 90 minutes Cmax in the blood is observed, amounting to 1.3 μg / ml. Compared with a single dose, when stable, Cmax of terbinafine is about 25% higher, with an increase in blood AUC by 2.3 times. Effective T½ approximately 30 hours. Eating slightly affects the bioavailability of Lamicon and does not require dose adjustment.

Terbinafine binds to plasma proteins by 99%. The drug quickly penetrates the dermis and accumulates in the stratum corneum. Stands out also sebaceous glands and in large concentrations found in the hair, hair folliclesand skin integument. In the first weeks of treatment penetrates into plate of nails.

Terbinafine metabolism is fast enough, with the participation of cytochrome P450. After the process biotransformationInactive metabolites of Lamicon are excreted mainly by the kidneys.

At pathologies of the kidneys and / or liver The rate of elimination of terbinafine slows down, which makes its concentration in the blood higher.

Indications for use

All local dosage forms of Lamicon (cream, spray, gel) are intended for the treatment of:

  • fungal lesionsskin caused by Microsporum mushrooms, Trichophyton, Epidermophyton(dermotophytosisgroin, feet, torso, etc.);
  • multi-colored (pityriasis) deprivingdue to exposure Malassezia mushrooms (Pityrosporum);
  • candidiasisskin provoked Candida mushrooms.

The oral form of the drug Lamicon - tablets is used for therapy:

  • fungal infections of the skin, in the case when the concentration of lesions, their prevalence or severity, is a sufficient reason for oral treatment;
  • scalp mycosis and onychomycosis(nail damage).

Tablets are not prescribed for therapy. multi-colored (pityriasis) depriving.


The only absolute contraindication to all dosage forms of Lamicon is hypersensitivityto its components: terbinafine or additional ingredients.

Periods pregnancy, breastfeeding and childhood are relative contraindications to taking Lamicon in all dosage forms.

Side effects

When using external forms of the drug, local reactions, such as: burningor peeling skin, itching, irritationand pain, pigmentation disordercrust formation erythemain the treated area and others. These reactions rarely lead to discontinuation of therapy and mostly go away on their own.

It is necessary to distinguish the above reactions from some possible similar ones. allergic manifestations: itching skin, hives, rashon the skin (including bullous), which are observed quite rarely, but often require discontinuation of treatment. In this regard, if any side effects are detected, the attending physician should be informed about this.

Also watched eye irritation in case of accidental ingestion of terbinafine in them.

In especially rare cases, it may worsen earlier latent fungal infection.

Therapy with Lamicon tablets is usually tolerated without serious side effects, although in some cases the following manifestations are possible:

Blood system:

  • agranulocytosis;
  • neutropenia;
  • pancytopenia;
  • thrombocytopenia.

The immune system:

  • Lyell's syndrome;
  • anaphylactoid reactions (including angioedema);
  • Stevens-Johnson syndrome;
  • systemic and skin symptoms lupus erythematosus;
  • photosensitization.

Nervous system:

  • taste disorders;
  • headache;
  • hypesthesia;
  • dizziness;
  • paresthesia.

Gastrointestinal organs:

  • a feeling of fullness in the stomach;
  • dyspepsia;
  • loss of appetite;
  • nausea;
  • diarrhea;
  • stomach ache.

Skin and subcutaneous tissue:

  • mild skin reactions (hives, rash);
  • exacerbation of psoriasis or psoriasis-like rashes;
  • acute exanthematous generalized pustulosis (rarely);
  • hair loss(with unproven causal relationship).

Musculoskeletal system:

  • myalgia;
  • arthralgia.

Hepatobiliary system:

  • increased levels of liver enzymes;
  • hepatobiliary dysfunction (mostly cholestatic);
  • individual cases have been described liver pathologies heavy character (jaundice, cholestasis, hepatitis).


  • feeling tired (very rare).

Instructions for use

The instruction for Lamicon spray, cream and gel involves the use of these dosage forms only externally. Before using external products, you should first clean and dry the affected areas of the skin.

Depending on the pathogen and the severity of the lesion, Lamicon cream, instructions for use recommends applying 1-2 times throughout the day. Spray Lamicon is also applied from 1 to 2 times, while Lamicon Dermgel is applied once a day.

Cream and gel are applied to affected skin and adjacent areas of the skin with a thin layer and rubbed lightly. In the event that infections are accompanied by diaper rash, for example in the inguinal region, between the fingers, under the mammary glands, between the buttocks, etc., the treated areas can be covered with gauze, especially at night.

Spray, in sufficient quantity for visible moisture, is sprayed onto skin areas affected by fungias well as on healthy skin.

The duration of treatment with the use of local funds, depending on its severity, usually takes from 7 to 14 days.

Relief of the symptoms of the disease is usually observed after a few days. For the effectiveness of therapy, it is necessary to strictly adhere to the regimen of application of drugs, do not miss another appliqueand do not discontinue treatment before the recommended period, as this can lead to relapse.

Elderly patients do not need dose adjustment of local drugs.

Lamicon tablets are prescribed for adults and children from 6 years old, with a weight of more than 20 kilograms. The intake of tablets continues for a time sufficient for complete disappearance symptom of disease, depending on its severity and nature.

The total dose of Lamicon in the form of tablets for adults is 250 mg, for children weighing 20 to 40 kilograms - 125 mg, over 40 kilograms - 250 mg.

Duration of treatment with candidiasis of the skin, trichophytosis skin and perineum, mainly from 2 weeks to 1 month, with dermatomycosis of the feet from 2 weeks to 1.5 months.

Fungal diseases of the scalp, most often found in children, respond to treatment in recommended doses for 4 weeks.

Therapy onychomycosisIt usually takes 1.5 months for fingernails, and 3 months for toenails. In case of reduced growth nail plates, the course of treatment may require a longer time.


Due to the small systemic absorption of the external forms of Lamicon, its overdose is unlikely. In case of accidental ingestion of local funds inside, as well as taking ultra-high doses of the oral form of the drug, manifestations are possible headaches, nausea, dizzinessand epigastric pain. In this case, you should artificially induce vomiting and wash the stomach.


Interactions of cream, gel and spray Lamicon with other drugs have not been identified.

When taking pills, an increase in blood clearance is possible terbinafine with the parallel use of inducers of its metabolism and a decrease in clearance when applied cytochrome P450 inhibitors. This combination of drugs requires dose adjustment of Lamicon.

Terbinafinedoes not affect clearance Digoxinor Antipyrine, increases 82% clearance Desipramineand 15% lower clearance Cyclosporin.

Rifampicindoubles clearance terbinafine.

Lamicon slightly affects the change (in one direction or another) of the clearance of drugs, metabolismwhich proceeds involving cytochrome P450, such as: Terfenadine, Tolbutamide, Triazolamor oral contraceptives.

Taking Lamicon tablets reduces the clearance of intravenously administered Caffeineby 19%.

Terbinafineable to suppress CYP 2D6-mediated metabolism, which may have clinical significance for drugs metabolized by this enzyme: β-adrenergic blockers, tricyclic antidepressantsSSRIs antiarrhythmic drugs MAO inhibitors.

Terms of sale

All dosage forms of Lamicon are dispensed after presentation of the prescription.

Storage conditions

Tablets, as well as external forms of the drug, are stored at temperatures up to 25 ° C.

Shelf life

For all forms - 24 months.

Special instructions

Cream, gel and spray Lamikon are intended exclusively for external application.

Avoid contact with external products in the eyes, and in case of accidental contact, rinse with enough running water.

In order to prevent mycotic reinfection it is necessary to regularly change the laundry, do not wear poorly breathable clothing or clothes that are too tight, thoroughly dry the problem areas after washing, always use a clean individual towel. Do not walk barefoot with mycosis of the feet. Spray socks, tights, etc., as well as the inside of the shoe.

Lamicon tablets are not recommended for patients with active or chronic liver damage.

Since the drug has some hepatotoxicity, liver status should be evaluated even in healthy patients.

Upon detection nauseaunknown etiology fatigue, anorexia, vomitingRight-sided abdominal pain jaundice, light stool or dark urine, the patient must inform his doctor about this and stop taking the pills. Then an assessment of the liver.

In case of increase skin rashes, therapy is canceled until the cause of these phenomena is clarified.

For any pathological change in blood, while taking Lamicon, you need to consider replacing the treatment.

With creatinine clearance less than 50 ml / min, oral administration is not recommended. terbinafine.


  • Amorolac;
  • Mycoseptin;
  • Mikolak;
  • Nitrofungin;
  • Exoderyl;
  • Salicylic acid.


  • Lamisil;
  • Mycofin;
  • Lamifen;
  • Terbizil;
  • Terbinafine;
  • Exifin;
  • Fungotek.

For children

Children are not recommended to use cream and spray until they are 12 years old, and dermgel until 18 years old.

Tablets are prescribed with extreme caution after the patient reaches the age of 6 years and weighs more than 20 kilograms.

In pregnancy (and lactation)

The drug Lamicon, both in tablets and in external forms, is used during pregnancy only in extreme cases and under the supervision of a doctor.

With any method of application terbinafineenters the milk of a nursing mother. Therefore, it is better to abandon breastfeeding during therapy with Lamicon.

Lamicon reviews

Reviews on the effectiveness of the external forms of the drug Lamicon (cream, spray, dermgel), if used against sensitive to terbinafinemushrooms, for the most part, are positive. The drug begins to act in a few days and leads to the complete disappearance of manifestations fungal diseaseby the end of the course of therapy, which most often lasts 7-14 days.

In the case of a severe lesion, for a more effective and quick treatment, it is preferable to use a combination of dosage forms of the drug, for example, taking tablets in parallel and applying a cream, spray or gel. For processing the inside of the shoe, in order to prevent RInfections also apply Lamicon spray. Reviews about the tablets of this drug, subject to all the recommendations of the doctor and taking into account the indications and contraindications, are also positive and indicate the high effectiveness of this drug.

Negative reviews of Lamicon, found on user forums, may be associated with the use of the drug for treatment insensitive to him mushroomsor improper use of its dosage forms. In the case earlier than the recommended time of interrupted therapy, even with a visible improvement, relapses of the disease are possible, and if personal hygiene rules associated with fungal infections are not observed, the mushrooms can spread to other parts of the body.

Therefore, if you suspect the presence of fungal infection it is necessary to precisely establish its pathogen to prescribe an adequate and effective, in this case, treatment, which can only be recommended by a dermatologist.

It is worth paying attention to the fact that on the Internet you can often find instructions for Lamicon ointment, a description of its action, reviews of the ointment, recommendations for its use, etc., which are not true. At this time, the Farmak company produces the drug Lamikon only in the form of a cream, spray, dermgel and tablets. All other described dosage forms of the drug are erroneous and most likely are the result of a misunderstanding of the differences between the foundations of ointment, cream and gel.

Lamicon price, where to buy

The cost of the drug Lamicon in Ukraine varies depending on its dosage form. On average, the cream can be purchased for 60 hryvnias, dermgel for 65 hryvnias and for 75 hryvnias Lamikon spray. The price of tablets of the drug varies from 130 to 160 hryvnia for 14 pieces.

  • Online pharmacies in UkraineUkraine
  • Online pharmacies in Kazakhstan


  • Lamicon 15 g cream PAT "Farmak", Ukraine80 UAH order
  • Lamicon 1% 25 g spray PAT "Farmak", Ukraine105 UAH order
  • Lamicon Dermgel 1% 15 g gel PAT "Farmak", Ukraine81 UAH order
  • Lamicon 0.25 g No. 14 tablets PAT "Farmak", Ukraine130 UAH to order

Pani Pharmacy

  • Lamicon cream Lamicon cream 1% 15g Ukraine, Farmak OJSC 86 UAH order
  • Lamicon Dermgel Gel Lamicon Dermgel Gel 1% Tube 15g Ukraine, Farmak OAO 96 UAH order
  • Lamicon liquid Lamicon spray 1% 25g Ukraine, Farmak OJSC 118 UAH order
  • Lamicon tablets Lamicon tablets 250mg No. 14 Ukraine, Farmak OAO 148 UAH order
show more


  • Lamicon 1% 15 g cream for external prim.Farmak (Ukraine) 1 tg.order
  • Lamikon 1% 25 g spray external Farmak (Ukraine) 1 tg.order
show more

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